Xylocaine® with Epinephrine 1% (1:100,000) Injection, USP, 50 mL Multiple-Dose Vial – Box (25/EA)

Product Specifications

Specification	Details
Manufacturer / Brand	Fresenius Kabi USA, LLC / Xylocaine®
Manufacturer # / SKU	63323048257
NDC Number	63323-0482-57
Active Ingredients	Lidocaine Hydrochloride (10 mg/mL) / Epinephrine (0.01 mg/mL)
Strength / Ratio	1% Lidocaine HCl with Epinephrine 1:100,000
Volume per Unit	50 mL
Container Type	Multiple-Dose Vial (MDV)
Formulation	Contains Methylparaben Preservative & Sodium Metabisulfite
Storage Temperature	20°C to 25°C (68°F to 77°F)
Packaging	Each / Box (25 Vials/EA)
Latex Content	Not made with natural rubber latex

Key Features & Clinical Applications

• Dual-Action Efficacy: Epinephrine causes localized vasoconstriction, which slows systemic absorption, extends the anesthetic block window, and minimizes localized bleeding.

• Red Color Coded: Visual identification features a bright red flip-top cap to help healthcare workers instantly identify the concentration and presence of epinephrine.

• Preserved Formulation: Contains 1 mg/mL of methylparaben to prevent microbial growth across multiple needle punctures.

• Extended Volume: The 50 mL vial capacity supports extensive infiltration blocks, large field blocks, or multiple small procedures within an active clinic day.

• Clinical Use: Highly utilized for local dermal infiltration, minor dermatological excisions, dental procedures, and peripheral nerve blocks.

⚠️ Usage Note: Do Not Autoclave. Because this formulation contains epinephrine, autoclaving will cause chemical degradation of the vasoconstrictor. Protect from light.

⚠️ Contraindications: Do not use if the solution turns a pinkish hue, darkens beyond a very light yellow, or develops a visible precipitate.

⚠️ Anatomical Warning: Use extreme caution when infiltrating areas supplied by end-arteries (e.g., fingers, toes, nose, ears, penis), as vasoconstriction from epinephrine can cause localized tissue ischemia or necrosis.