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Telmisartan Tablets, USP, 40 mg, 30 Count Bottle
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Telmisartan Tablets, USP, 40 mg, 30 Count Bottle

SKU ASL 704330

$6.50

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Brand
Ascend Laboratories LLC

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Product details

Product Specifications

Specification Details
Manufacturer / Brand Ascend Laboratories, LLC
Manufacturer # / SKU 7043302401 or 67877048330
NDC Number 70433-024-01 or 67877-483-30
Active Ingredient Telmisartan 40 mg
Application Antihypertensive
Dosage Form Tablet
Strength 40 mg
Color / Shape White to Off-White / Oval
Markings "T" and "40" on one side
Packaging / Sold As Bottle of 30 Tablets
Storage Requirements USP Controlled Room Temperature 20°C to 25°C
UNSPSC Code 51101803

Key Features

  • Long Half-Life: Features an exceptionally long terminal elimination half-life (approx. 24 hours), allowing for effective 24-hour blood pressure control with a single daily dose.

  • Selective Receptor Binding: High affinity for the AT-1 receptor with no affinity for the AT-2 receptor, ensuring targeted cardiovascular action.

  • Cardiovascular Risk Reduction: Indicated for the reduction of the risk of myocardial infarction, stroke, or death from cardiovascular causes in patients 55 years of age or older at high risk.

  • No Cough Side Effect: Unlike ACE inhibitors, Telmisartan does not inhibit ACE (kininase II) and does not lead to the accumulation of bradykinin, significantly reducing the incidence of dry cough.

  • Moisture-Protected Packaging: Often provided in high-barrier packaging to protect the hygroscopic nature of the tablets.

Clinical Applications

  • Hypertension: Used alone or in combination with other antihypertensive agents to treat high blood pressure.

  • Cardiovascular Risk Reduction: Indicated for patients unable to take ACE inhibitors who are at high risk for major cardiovascular events.

  • Diabetic Nephropathy: Often used off-label to provide renal protection in hypertensive patients with type 2 diabetes.

⚠️ Usage Note: Telmisartan should be taken once daily. It can be administered with or without food.

⚠️ Black Box Warning: Drugs that act directly on the renin-angiotensin system can cause injury and death to the developing fetus. Discontinue as soon as pregnancy is detected.

⚠️ Safety: Monitor serum potassium levels regularly, especially in elderly patients or those with renal impairment, as ARBs can cause hyperkalemia.